Author
University of British Columbia
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Dominic Skitsko, Beatrice M. Tam, Colette N. Chiu…·Orson L. Moritz
The paper examines the effects of GNAT1 mutations in Xenopus laevis, showing altered phototransduction timing, dark adaptation, and GNAT1 trafficking in different genetic backgrounds.
Colette N. Chiu, Beatrice M. Tam, Paloma Burns, Orson L. Moritz
Aaron D. Loewen, Beatrice M. Tam, Colette N. Chiu…·Orson L. Moritz
This study examines RHO mutations in 26 RP models, finding that some cause light-dependent degeneration and others involve proteolytic cleavage and mislocalization.
Beatrice M. Tam, Paloma Burns, Colette N. Chiu, Orson L. Moritz
This study investigates how T4K rhodopsin causes light-exacerbated retinal degeneration in Xenopus laevis, showing that photoactivation is toxic and that cell death is mitigated by interactions with phototransduction proteins.