Author

Benjamin A. Clarke

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

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Colleen Byrnes· 1 shared Hongling ZhuiD· 1 shared Mari KonoiD· 1 shared Richard L. ProiaiD· 1 shared Saurav MajumderiD· 1 shared

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2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Colleen Byrnes

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintDec 8, 2025

1-Deoxysphingolipids Require Very-Long-Chain Ceramide Synthesis to Induce ER Stress and Neurotoxicity

Colleen Byrnes, Benjamin A. Clarke, Hongling Zhu…·Richard L. Proia

This study identifies a pathway involving very-long-chain ceramide synthesis that is essential for 1-deoxysphinganine-induced ER stress and neurotoxicity in SH-SY5Y cells.

1 citation

humanproteomics

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