Cell BiologyCell Death and DiseasePeer-reviewed
Longitudinal analysis of retinal cell state transitions in RB1-deficient retinal organoids reveals the nascent cone precursors are the earliest cell-origin of human retinoblastoma
Ke Ye, Yuan Wang, Ping Xu…·Xiufeng Zhong
This study identifies ATOH7+ nascent cone precursors as the earliest cell-of-origin for human retinoblastoma using RB1-deficient retinal organoids and scRNA-seq.