Author
Bingrun Liu
Whitehead Institute for Biomedical Research
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Biology Disciplines
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2024-2024 · peak 2/yrCo-Author Collaboration Network
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- Developmental BiologyDevelopmentPeer-reviewed
Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cells
Natalie G. Pfaltzgraff, Bingrun Liu, Dirk G. de Rooij…·Maria M. Mikedis
The paper shows that the MEIOC-YTHDC2-RBM46 complex destabilizes mRNAs of transcriptional repressors in mouse spermatogenic cells, enhancing their competence to initiate meiosis in response to retinoic acid.