Developmental BiologybioRxivPreprint
Foxd3 controls heterochromatin-mediated silencing of repeat elements in mouse embryonic stem cells and represses the 2-cell transcription program
Deepika Puri, Birgit Koschorz, Bettina Engist…·Thomas Montavon
This study identifies FOXD3 as a regulator of repeat element transcription in mouse embryonic stem cells, showing it represses 2-cell state genes and repeat sequences by promoting heterochromatin formation.
DOI 10.1101/2021.05.01.442081