Author

Bradley J. Backes

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexis N. BrumwelliD· 1 shared Dean SheppardiD· 1 shared Dustin J. MalyiD· 1 shared Feroz R. PapaiD· 1 shared Gayani Perara· 1 shared Harold A. ChapmaniD· 1 shared Maike Thamsen· 1 shared Rajarshi GhoshiD· 1 shared

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2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Alexis N. BrumwellORCID

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1 paper

Recent·Most cited

Molecular BiologyPLoS ONEPeer-reviewedJan 9, 2019

Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung

Maike Thamsen, Rajarshi Ghosh, Vincent C. Auyeung…·Feroz R. Papa

This study shows that inhibiting IRE1α kinase/RNase reduces lung fibrosis in mice by blocking the terminal UPR, with two compounds demonstrating efficacy in preventing and reversing fibrosis.

65 citationstop 4%

mouseexperimental assay

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