BiochemistrybioRxivPreprint
Functional Reconstitution of Human OATP1B1 and OATP1B3 in Proteoliposomes: Effect of Bicarbonate Gradients and Substrate-specific Stimulation on Transport
Juan Carlos Mellado Tenorio, Stephen J. Butler, Bruno Stieger, Kaspar P Locher
This study reconstitutes OATP1B1 and OATP1B3 in proteoliposomes to show bicarbonate gradients drive substrate uptake, with EGCG enhancing OATP1B3 transport.
DOI 10.64898/2026.10.29.762842