Author

C. A. Horton

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. A. Shrikumar· 1 shared A. Afek· 1 shared A. K. Aditham· 1 shared A. Kundaje· 1 shared A. M. Alexandari· 1 shared E. Marklund· 1 shared J. M. Schaepe· 1 shared J. Zeitlinger· 1 shared

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2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. A. Shrikumar

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1 paper

Recent·Most cited

BiophysicsbioRxivMay 24, 2022

Short tandem repeats bind transcription factors to tune eukaryotic gene expression

C. A. Horton, A. M. Alexandari, M. G. B. Hayes…·P. M. Fordyce

This study shows STRs modulate TF-DNA interactions by altering binding affinities and on rates, impacting gene expression through increased TF density near target sites.

DOI 10.1126/science.add1250

DNA methylationChIP-seq

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