Author

C. A. Sibbald

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Biophysics· 1

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

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G. R. Bowman· 1 shared J. R. Porter· 1 shared K. E. Moeder· 1 shared K. M. Hart· 1 shared M. I. Zimmerman· 1 shared M. J. Greenberg· 1 shared

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2018-2018 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

G. R. Bowman

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1 paper

Recent·Most cited

BiophysicsbioRxivSep 18, 2018

Cooperative changes in solvent exposure identify cryptic pockets, conformational switches, and allosteric coupling

J. R. Porter, K. E. Moeder, C. A. Sibbald…·G. R. Bowman

The paper introduces a method to identify functionally-relevant conformational changes in proteins by analyzing cooperative solvent exposure changes, demonstrating its utility in discovering cryptic allosteric sites.

DOI 10.1107/s0108767319095795

protein structuredeep learning

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