CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids
M. Lo, A. Sharir, M. D. Paul, H. Torosyan, C. Agnew, D. R. Raleigh, N. Jura, O. D. Klein
This study identifies CNPY4 as a negative regulator of the Hedgehog pathway by modulating membrane sterol lipid levels, revealing a new mechanism of pathway regulation.
bioRxiv · Mar 15, 2021Biochemistry