Author

C. Blaukopf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

D. W. Gerlich· 4 shared B. A. Gibson· 2 shared C. C. H. Langer· 2 shared J.-M. Peters· 2 shared L. K. Doolittle· 2 shared M. K. Rosen· 2 shared G. Narlikar· 1 shared I. J. Finkelstein· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersCell Biology

D. W. Gerlich

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4 papers

Recent·Most cited

Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase

P. Batty, C. C. H. Langer, Z. Takacs, W. Tang, C. Blaukopf, J.-M. Peters, D. W. Gerlich

This study shows cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase, independent of condensins, suggesting loop extrusion is a general mechanism for genome segregation.

bioRxiv · Jan 12, 2023Cell Biology

In Diverse Conditions Intrinsic Chromatin Condensates Have Liquid-like Material Properties

B. A. Gibson, C. Blaukopf, T. Lou, L. K. Doolittle, I. J. Finkelstein, G. Narlikar, D. W. Gerlich, M. K. Rosen

This study shows that intrinsic chromatin condensates exhibit liquid-like properties under diverse conditions, challenging previous claims of their solidity.

bioRxiv · Nov 22, 2021 · PreprintBiophysics

A chromatin phase transition protects mitotic chromosomes against microtubule perforation

M. W. G. Schneider, B. A. Gibson, S. Otsuka, M. F. D. Spicer, M. Petrovic, C. Blaukopf, C. C. H. Langer, L. K. Doolittle, M. K. Rosen, D. W. Gerlich

This study shows that global histone deacetylation during mitosis induces a chromatin phase transition that protects chromosomes from microtubule perforation and ensures proper segregation.

bioRxiv · Jul 5, 2021 · PreprintCell Biology

Dynamics of sister chromatid resolution during cell cycle progression

R. Stanyte, J. Nuebler, C. Blaukopf, R. Hoefler, R. Stocsits, J.-M. Peters, D. W. Gerlich

This study investigates sister chromatid organization in live human cells, finding that sister loci separate during G2 phase and equilibrate within dynamic chromatin polymers, challenging the notion of persistent cohesin sites.

bioRxiv · Mar 16, 2018Cell Biology