Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation.
S. Trova, F. Lin, S. Lomada, M. Fenton, B. Chauhan, A. Adams, A. Puri, A. Di Maio, T. Wieland, D. Sewell, K. Dick, D. Wiseman, D. P. Wilks, M. Goodall, M. T. Drayson, , C. Bunce
This study shows that pathogen and human NDPK-proteins promote AML cell survival by activating the NLRP3-inflammasome in monocytes.
bioRxiv · Jan 2, 2023Microbiology