Interferon-sensitized hematopoietic progenitors dynamically alter organismal immunity
M. Guillamot, I. Subudhi, V. Paraskevopoulou, A. Prystupa, I. Sidhu, A. Yeaton, M. Laskou, C. Hannemann, C. Donahoe, D. Wiseman, I. Aifantis, S. Naik, A. Weinstock
This study shows that transient skin inflammation activates hematopoietic stem/progenitor cells via type I interferon, altering systemic immunity and affecting atherosclerosis and influenza outcomes.
bioRxiv · Apr 24, 2024Immunology