Cell BiologybioRxiv
Structures of the interleukin 11 signalling complex reveal dynamics of gp130 extracellular domains and the inhibitory mechanism of a cytokine variant
R. D. Metcalfe, E. Hanssen, K. Y. Fung…·M. D. W. Griffin
This study presents cryo-EM and crystal structures of the IL-11 signalling complex, revealing dynamics of gp130 and the inhibitory mechanism of a cytokine variant.