Author

C. C. Ritch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. K. Sorger· 3 shared S. Santagata· 3 shared G. Gaglia· 2 shared H. Pfister· 2 shared J.-R. Lin· 2 shared M. Burger· 2 shared R. Krueger· 2 shared S. Coy· 2 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCancer Biology

P. K. Sorger

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Author profile →

3 papers

Recent·Most cited

Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

G. Gaglia, M. Burger, C. C. Ritch, D. Rammos, Y. Dai, G. E. Crossland, S. Z. Tavana, S. Warchol, A. M. Jaeger, S. Naranjo, S. Coy, A. Johnson, R. Krueger, J.-R. Lin, H. Pfister, , S. Santagata

The paper maps lymphocyte interactions in lung adenocarcinoma using spatial analysis and machine learning, revealing dynamic lymphocyte networks that support anti-tumor immune responses.

bioRxiv · Aug 11, 2022Cancer Biology

Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data

S. Warchol, R. Krueger, A. J. Nirmal, G. Gaglia, J. Jessup, C. C. Ritch, J. Hoffer, J. L. Muhlich, M. Burger, T. L. Jacks, S. Santagata, P. K. Sorger, H. Pfister

Visinity analyzes spatial cell interactions in multiplexed tissue images to identify biological processes and immune-tumor interactions.

bioRxiv · May 9, 2022Cell Biology

Single Cell Spatial Analysis Reveals the Topology of Immunomodulatory Purinergic Signaling in Glioblastoma

S. Coy, S. Wang, S. A. Stopka, J.-R. Lin, R. Rashid, C. Yapp, C. C. Ritch, P. Khadka, M. Regan, J. Hwang, P. Y. Wen, P. Bandopadhayay, K. L. Ligon, N. Y. Agar, P. K. Sorger, , S. Santagata

The paper uses spatial single-cell analysis to show that CD73 and CD39 expression in glioblastoma correlates with poor clinical outcomes and immunosuppressive signaling.

bioRxiv · Jan 12, 2022Cancer Biology