The ULK1-FBXW5-SEC23B nexus controls autophagy
M. Pagano, Y.-T. Jeong, D. Simoneschi, S. Keegan, D. Melville, N. Adler, A. Saraf, L. Florens, M. P. Washburn, C. Cavasotto, D. Fenyö, A. M. Cuervo, M. Rossi
This study identifies the ULK1-FBXW5-SEC23B pathway as a regulator of autophagy by controlling COPII localization and SEC23B stability during nutrient starvation.
bioRxiv · Oct 12, 2018Cell Biology