Author

N. Adler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Cuervo· 1 shared A. Saraf· 1 shared A. T. Bahcheli· 1 shared C. Cavasotto· 1 shared D. Fenyö· 1 shared D. Melville· 1 shared D. Pellegrina· 1 shared D. Schramek· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. M. Cuervo

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Author profile →

2 papers

Recent·Most cited

Mutational processes of tobacco smoking and APOBEC activity generate protein-truncating mutations in cancer genomes

N. Adler, A. T. Bahcheli, K. Cheng, K. N. Al-Zahrani, M. Slobodyanyuk, D. Pellegrina, D. Schramek, J. Reimand

The paper analyzes the impact of mutational signatures from tobacco smoking and APOBEC activity on protein-truncating mutations in 12,341 cancer genomes across 18 types, showing their enrichment in key cancer pathways and tumor suppressors.

bioRxiv · Mar 19, 2023Cancer Biology

The ULK1-FBXW5-SEC23B nexus controls autophagy

M. Pagano, Y.-T. Jeong, D. Simoneschi, S. Keegan, D. Melville, N. Adler, A. Saraf, L. Florens, M. P. Washburn, C. Cavasotto, D. Fenyö, A. M. Cuervo, M. Rossi

This study identifies the ULK1-FBXW5-SEC23B pathway as a regulator of autophagy by controlling COPII localization and SEC23B stability during nutrient starvation.

bioRxiv · Oct 12, 2018Cell Biology