Cell BiologybioRxivPreprint
Cingulin unfolds ZO-1 and organizes myosin-2B and gamma-actin to mechanoregulate apical and tight junction membranes
E. Vasileva, F. Rouaud, D. Spadaro…·S. Citi
This study shows cingulin regulates apical and tight junction membrane mechanics by organizing myosin-2B and gamma-actin and modulating ZO-1 conformation in MDCK cells.