Author

C. Choudhary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Al-Fatlawi· 1 shared A. F. Stewart· 1 shared A. Gupta· 1 shared A. Kranz· 1 shared A. R. Poetsch· 1 shared A. Zutz· 1 shared B. Weinert· 1 shared C. Schölz· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. Al-Fatlawi

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4 papers

Recent·Most cited

A systems-scale, integrated view of the ubiquitylation site occupancy and dynamics

G. Prus, S. Satpathy, B. Weinert, T. Narita, C. Choudhary

This paper quantifies ubiquitylation site occupancy and turnover rates, revealing their relationship to phosphorylation and identifying a surveillance mechanism protecting E1/E2 enzymes.

bioRxiv · Jul 19, 2023 · PreprintBiochemistry

The BOD1L subunit of the SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

G. Ciotta, S. Singh, A. Kranz, A. Gupta, D. C. Torres, J. Fu, R. Choudhury, N. Liske, W. K. Chu, C. Choudhary, L. Gahurova, D. Severinov, A. Al-Fatlawi, M. Schroeder, R. Aasland, , A. F. Stewart

The paper shows that BOD1L in the SETD1A complex maintains DNA repair gene expression despite reducing H3K4 trimethylation, and its loss causes DNA damage and cell death in ESCs.

bioRxiv · Apr 6, 2023 · PreprintCell Biology

Histone deacetylase inhibitors butyrate and bufexamac inhibit de novo HIV-1 infection in CD4 T-cells

C. Schölz, L. Chen, A. Zutz, O. T. Keppler, J. Philippou-Massier, H. Blum, T. Liebner, C. Choudhary

This study shows that HDAC inhibitors butyrate and bufexamac inhibit de novo HIV-1 infection in CD4 T-cells without reactivating latent virus.

bioRxiv · Apr 29, 2020 · PreprintMicrobiology

The dynamic equilibrium of nascent and parental MCMs safeguards replicating genomes

H. Sedlackova, M.-B. D. Rask, R. Gupta, C. Choudhary, K. Somyajit, J. Lukas

This paper investigates how MCM2-7 complexes are maintained across cell divisions to ensure genome stability, finding that MCMBP facilitates the nuclear import of nascent MCM3-7 subunits to sustain pre-RC formation.

bioRxiv · Nov 2, 2019Cell Biology