Author

C. D. Warren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. Wang· 1 shared A. Flory· 1 shared A. L. McCleary-Wheeler· 1 shared A. Phelps-Dunn· 1 shared A. R. Griswold· 1 shared B. F. Cravatt· 1 shared B. Melillo· 1 shared C. Webster· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. E. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Covalent Targeting of Splicing in T Cells.

K. A. Scott, H. Kojima, N. Ropek, C. D. Warren, T. L. Zhang, S. J. Hogg, C. Webster, X. Zhang, J. Rahman, B. Melillo, B. F. Cravatt, J. Lyu, O. Abdel-Wahab, E. V. Vinogradova

This study develops chemical probes to target splicing factors in T cells, showing state-dependent loss of ITK via SF3B1 and demonstrating covalent ligandability of splicing regulators.

bioRxiv · Dec 18, 2023Immunology

Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of over 3,000 dogs: determining the optimal age to initiate cancer screening in canine patients

J. M. Rafalko, K. M. Kruglyak, A. L. McCleary-Wheeler, V. Goyal, A. Phelps-Dunn, L. K. Wong, C. D. Warren, G. Brandstetter, M. C. Rosentel, L. M. McLennan, D. S. Grosu, J. Chibuk, D. W. Tsui, I. Chorny, A. Flory

This study determines the optimal age to start cancer screening in dogs by analyzing age at diagnosis across breeds, weight, sex, and cancer type in over 3,000 dogs.

bioRxiv · Mar 30, 2022Cancer Biology

Oxidized thioredoxin-1 restrains the NLRP1 inflammasome

D. P. Ball, A. E. Wang, C. D. Warren, Q. Wang, A. R. Griswold, S. D. Rao, D. A. Bachovchin

This study identifies oxidized thioredoxin-1 as a repressor of NLRP1 inflammasome activation, showing that mutations impair this interaction and cause autoinflammatory disease.

bioRxiv · Sep 20, 2021Immunology