Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
D. P. Ball, A. E. Wang, C. D. Warren…·D. A. Bachovchin
This study identifies oxidized thioredoxin-1 as a repressor of NLRP1 inflammasome activation, showing that mutations impair this interaction and cause autoinflammatory disease.
E. L. Orth-He, H.-C. Huang, S. D. Rao…·D. A. Bachovchin
This study identifies cytosolic peptide accumulation as a danger signal that activates NLRP1 and CARD8 inflammasomes by promoting NT degradation and disrupting DPP9-mediated sequestration of CT fragments.
D. P. Ball, C. Y. Taabazuing, A. R. Griswold…·D. A. Bachovchin
This study shows that pro-caspase-1 autoproteolysis is required for both ASC-dependent and -independent inflammasome activation in human cells.