Author

C. De Virgilio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Nicastro· 3 shared A. A. Teleman· 1 shared A. Lamprakis· 1 shared C. Demetriades· 1 shared E. Fernandez-Garcia· 1 shared F. Tripodi· 1 shared G. Figlia· 1 shared H. Gaillard· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

R. Nicastro

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 6, 2022

Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor

R. Nicastro, L. Brohee, J. Alba…·C. Demetriades

The paper shows malonyl-CoA inhibits mTORC1 by competing with ATP, linking lipid biosynthesis to cellular growth regulation in yeast and mammals.

DOI 10.1101/2022.11.06.515351

𝕏 PostBluesky

BiochemistrybioRxivOct 18, 2022

Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation

M. Caligaris, R. Nicastro, Z. Hu…·C. De Virgilio

This study shows Snf1/AMPK inhibits TORC1 during glucose starvation via Pib2 and Sch9 phosphorylation, integrating glucose and glutamine signals to regulate cell growth.

DOI 10.7554/elife.84319

yeastproteomics

𝕏 PostBluesky

Cell BiologyeLifePeer-reviewedJul 29, 2022

Manganese is a Physiologically Relevant TORC1 Activator in Yeast and Mammals.

R. Nicastro, H. Gaillard, L. Zarzuela…·R. E. Wellinger

This paper shows that manganese activates TORC1 in yeast and mammals, with implications for disease and aging.

DOI 10.7554/elife.80497

𝕏 PostBluesky