Author

C. Di

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

D. Enard· 2 shared A. Larracuente· 1 shared C. Ying· 1 shared D. M. Cucura· 1 shared D. Salazar Tortosa· 1 shared G. C. Conant· 1 shared H. An· 1 shared J. C. Pires· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersEvolutionary Biology

D. Enard

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4 papers

Recent·Most cited

Stability evolution as a major mechanism of human protein adaptation in response to viruses

C. Di, J. Murga-Moreno, D. Enard

The paper investigates stability evolution as a mechanism for virus-driven adaptation in human proteins, finding stability changes are more common in virus-interacting proteins than previously thought.

bioRxiv · Dec 1, 2022 · PreprintEvolutionary Biology

Decreased adaptation at human disease genes as a possible consequence of interference between advantageous and deleterious variants

C. Di, D. Salazar Tortosa, M. E. Lauterbur, D. Enard

The paper compares selective sweeps between disease and non-disease genes across populations, finding disease genes have fewer sweeps, likely due to interference from deleterious variants.

bioRxiv · Mar 31, 2021Evolutionary Biology

Genes derived from ancient polyploidy have higher genetic diversity and are associated with domestication in Brassica rapa

X. Qi, H. An, T. E. Hall, C. Di, P. Blischak, M. T. W. McKibben, Y. Hao, G. C. Conant, J. C. Pires, M. S. Barker

The paper identifies candidate genes associated with domestication in Brassica rapa and finds that genes from ancient polyploidy are more diverse and linked to domestication.

bioRxiv · Oct 15, 2020Plant Biology

Identification and quantification of Lyme pathogen strains by deep sequencing of outer surface protein C (ospC) amplicons

L. Di, Z. Wan, S. Akther, C. Ying, A. Larracuente, L. Li, C. Di, R. Nunez, D. M. Cucura, N. L. Goddard, K. Krampis, W. Qiu

The paper develops a deep sequencing method to identify and quantify Lyme pathogen strains by analyzing the ospC gene in ticks, revealing mixed infections and a new strain related to Borreliella bissettiae.

bioRxiv · Jun 4, 2018Microbiology