MTX-COVAB, a human-derived antibody with potent neutralizing activity against SARS-CoV-2 infection in vitro and in a hamster model of COVID-19
C. Esslinger, S. Schmitt, M. Weber, M. Hillenbrand, J. Seidenberg, A. Zingg, C. Townsend, B. Eicher, J. Rutkauskaite, P. Riese, C. A. Guzman, K. Fischer
The paper identifies a human-derived monoclonal antibody, MTX-COVAB, with potent neutralizing activity against SARS-CoV-2 in vitro and in a hamster model, showing efficacy against variants and readiness for clinical testing.
bioRxiv · Dec 1, 2020 · PreprintImmunology