Author

C. Fierke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Karasik· 1 shared A. Ramamoorthy· 1 shared A. Stoddard· 1 shared B. Sahoo· 1 shared G. Anantharamaiah· 1 shared J. Nowick· 1 shared M. Bekier· 1 shared M. Koutmos· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Karasik

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Author profile →

2 papers

Recent·Most cited

Apolipoprotein A-I Mimetic 4F Peptide Generates Amyloid Cytotoxins by Forming Hetero-oligomers with β-amyloid

B. Sahoo, M. Bekier, Z. Liu, V. Kocman, A. Stoddard, G. Anantharamaiah, J. Nowick, C. Fierke, Y. Wang, A. Ramamoorthy

The paper investigates how the 4F peptide interacts with β-amyloid to form toxic heteromers, reducing aggregation kinetics and increasing neurotoxicity.

bioRxiv · Aug 4, 2019 · PreprintBiophysics

Interplay between substrate recognition, 5’ end tRNA processing and methylation activity of human mitochondrial RNase P

A. Karasik, C. Fierke, M. Koutmos

This study shows that mtRNase P subunits synergistically recognize, cleave, and methylate some mitochondrial pre-tRNAs, with MRPP1/2 methylation activity enhanced by MRPP3.

bioRxiv · Oct 25, 2018Biochemistry