Apolipoprotein A-I Mimetic 4F Peptide Generates Amyloid Cytotoxins by Forming Hetero-oligomers with β-amyloid
B. Sahoo, M. Bekier, Z. Liu, V. Kocman, A. Stoddard, G. Anantharamaiah, J. Nowick, C. Fierke, Y. Wang, A. Ramamoorthy
The paper investigates how the 4F peptide interacts with β-amyloid to form toxic heteromers, reducing aggregation kinetics and increasing neurotoxicity.
bioRxiv · Aug 4, 2019 · PreprintBiophysics