BiochemistrybioRxiv
Optimization of pyrazolopyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor
A. Kraemer, C. G. Kurz, B.-T. Berger…·T. Hanke
This paper describes the optimization of pyrazolopyrimidine compounds to develop a highly selective and potent CK2 inhibitor, IC20, with high in vitro potency and exclusive selectivity.
DOI 10.1016/j.ejmech.2020.112770