Alterations of the TGFb-sequestration complex member ADAMTSL1 levels are associated with muscular defects and rhabdomyosarcoma aggressiveness
A. Bertrand-Chapel, S. Meyer, G. Juban, A. E. M. Kneppers, P. Huchede, C. Gallerne, R. Benayoun, E. Cohen, A. Lopez-Gonzalez, S. B. Larbi, M. Creveaux, L. Vaille, A. Bouvier, M. Theodore, L. Broutier, , M. CASTETS
This study shows ADAMTSL1 is involved in skeletal muscle regeneration and acts as a prognostic factor in aggressive rhabdomyosarcoma, correlating with a neural-like phenotype.
bioRxiv · Mar 7, 2023 · PreprintCancer Biology