Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation
K. P. Hoefig, A. Reim, C. Gallus, E. H. Wong, G. Behrens, C. Conrad, M. Xu, T. Ito-Kureha, K. Defourny, A. Geerlof, J. Mautner, S. M. Hauck, D. Baumjohann, R. Feederle, M. Mann, , V. Heissmeyer
The paper identifies the core RNA-binding protein (RBP)ome in human and mouse T helper cells, revealing new regulators of post-transcriptional gene regulation, including Celf1 as a Roquin-1-dependent coregulator of Icos.
bioRxiv · Aug 20, 2020 · PreprintImmunology