Author

C. Goosmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

V. Brinkmann· 4 shared E. A. Levashina· 2 shared G. Costa· 2 shared A. E. Hauser· 1 shared A.E. Hauser· 1 shared C. Chumduri· 1 shared C. Kreschel· 1 shared D. Eyermann· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersMicrobiology

V. Brinkmann

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria

M. Halte, E. P. Andrianova, C. Goosmann, F. F. V. Chevance, K. T. Hughes, I. B. Zhulin, M. Erhardt

The paper identifies FlhE as a periplasmic chaperone that prevents the formation of periplasmic flagella in Salmonella, which disrupts cell wall synthesis and causes cell lysis.

bioRxiv · Mar 11, 2024 · PreprintMicrobiology

Generation of a Plasmodium falciparum reporter line for studies of parasite biology throughout the life cycle

P. Suarez-Cortes, G. Costa, M. Andres, D. Eyermann, C. Kreschel, L. Spohr, C. Goosmann, V. Brinkmann, E. A. Levashina

This paper generates a new fluorescent reporter parasite strain, PfOBC13GFP, for studying Plasmodium falciparum throughout its life cycle with improved fluorescence and mosquito infectivity.

bioRxiv · May 23, 2023 · PreprintMicrobiology

Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

S. Koster, R. K. Gurumurthy, H. Berger, M. Drabkina, H.-J. Mollenkopf, C. Goosmann, V. Brinkmann, Z. Nagel, M. Mangler, T. F. Meyer, C. Chumduri

This study shows that Chlamydia coinfection with HPV disrupts cellular and genomic integrity safeguards in ectocervical organoids, promoting neoplastic progression.

bioRxiv · Apr 15, 2021 · PreprintCancer Biology

Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging

M. S. Severo, J. J. M. Landry, R. L. Lindquist, C. Goosmann, V. Brinkmann, P. Collier, A. E. Hauser, V. Benes, J. Henriksson, S. A. Teichmann, E. A. Levashina

The paper uses single-cell genomics and imaging to classify mosquito blood cells, revealing transcriptional signatures and challenges to current morphology-based classification.

bioRxiv · Dec 22, 2017Immunology

Non-competitive resource exploitation within-mosquito shapes evolution of malaria virulence

G. Costa, M. Gildenhard, M. Eldering, R.L. Lindquist, A.E. Hauser, R. Sauerwein, C. Goosmann, V. Brinkmann, E.A. Levashina

This study shows that mosquito lipid trafficking affects Plasmodium virulence by shaping sporozoite development and metabolic activity, revealing a vector-driven mechanism in malaria virulence evolution.

bioRxiv · Oct 27, 2017 · PreprintEvolutionary Biology