Author

S. Koster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Chumduri· 3 shared H. Berger· 3 shared M. Mangler· 3 shared T. F. Meyer· 3 shared H.-J. Mollenkopf· 2 shared R. K. Gurumurthy· 2 shared V. Brinkmann· 2 shared A. Quevedo-Olmos· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

C. Chumduri

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids

J. Dong, D. Holthaus, C. Peters, S. Koster, M. Ehsani, A. Quevedo-Olmos, H. Berger, M. Zarobkiewicz, M. Mangler, R. Kumar Gurumurthy, N. Hedemann, C. Chumduri, D. Kabelitz, T. F. Meyer

This study evaluates γδ T cell-mediated cytotoxicity against cervical organoids, finding that HPV-transformed and cancerous organoids are more susceptible than healthy ones.

bioRxiv · Jul 25, 2023Immunology

Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

S. Koster, R. K. Gurumurthy, H. Berger, M. Drabkina, H.-J. Mollenkopf, C. Goosmann, V. Brinkmann, Z. Nagel, M. Mangler, T. F. Meyer, C. Chumduri

This study shows that Chlamydia coinfection with HPV disrupts cellular and genomic integrity safeguards in ectocervical organoids, promoting neoplastic progression.

bioRxiv · Apr 15, 2021 · PreprintCancer Biology

Fatty acid oxidation impairs macrophage effector functions that control Mycobacterium tuberculosis

P. Chandra, L. He, M. Zimmerman, G. Yang, S. Koster, M. Ouimet, H. Wang, K. J. Moore, V. Dartois, J. D. Schilling, J. A. Philips

This study shows that blocking fatty acid oxidation in macrophages enhances their ability to control Mycobacterium tuberculosis infection by boosting reactive oxygen species and xenophagy.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology

Transition of Wnt signaling microenvironment delineates the squamo-columnar junction and emergence of squamous metaplasia of the cervix

C. Chumduri, R. K. Gurumurthy, H. Berger, S. Koster, V. Brinkmann, U. Klemm, H.-J. Mollenkopf, H. Herbst, M. Mangler, T. F. Meyer

The paper identifies that Wnt signaling dynamics in the stroma regulate the squamo-columnar junction and the emergence of squamous metaplasia in the cervix, without a localized stem cell population at the boundary.

bioRxiv · Oct 16, 2018Cancer Biology