Author

C. Chumduri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. Berger· 3 shared M. Mangler· 3 shared S. Koster· 3 shared T. F. Meyer· 3 shared H.-J. Mollenkopf· 2 shared R. K. Gurumurthy· 2 shared V. Brinkmann· 2 shared A. Quevedo-Olmos· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

H. Berger

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Author profile →

3 papers

Recent·Most cited

γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids

J. Dong, D. Holthaus, C. Peters, S. Koster, M. Ehsani, A. Quevedo-Olmos, H. Berger, M. Zarobkiewicz, M. Mangler, R. Kumar Gurumurthy, N. Hedemann, C. Chumduri, D. Kabelitz, T. F. Meyer

This study evaluates γδ T cell-mediated cytotoxicity against cervical organoids, finding that HPV-transformed and cancerous organoids are more susceptible than healthy ones.

bioRxiv · Jul 25, 2023Immunology

Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

S. Koster, R. K. Gurumurthy, H. Berger, M. Drabkina, H.-J. Mollenkopf, C. Goosmann, V. Brinkmann, Z. Nagel, M. Mangler, T. F. Meyer, C. Chumduri

This study shows that Chlamydia coinfection with HPV disrupts cellular and genomic integrity safeguards in ectocervical organoids, promoting neoplastic progression.

bioRxiv · Apr 15, 2021 · PreprintCancer Biology

Transition of Wnt signaling microenvironment delineates the squamo-columnar junction and emergence of squamous metaplasia of the cervix

C. Chumduri, R. K. Gurumurthy, H. Berger, S. Koster, V. Brinkmann, U. Klemm, H.-J. Mollenkopf, H. Herbst, M. Mangler, T. F. Meyer

The paper identifies that Wnt signaling dynamics in the stroma regulate the squamo-columnar junction and the emergence of squamous metaplasia in the cervix, without a localized stem cell population at the boundary.

bioRxiv · Oct 16, 2018Cancer Biology