Cancer BiologybioRxiv
Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities
M. Yousefi, G. Boross, C. Weiss…·M. M. Winslow
This study identifies RAS/PI3K pathway activation as a common driver in oncogene-negative lung adenocarcinomas and shows these tumors are vulnerable to targeted therapy.
DOI 10.1158/0008-5472.can-22-0059