C. Weiss

antiCD49d Ab treatment ameliorates age-associated inflammatory response and mitigates CD8 T cell cytotoxicity after traumatic brain injury

This study shows that anti-CD49d antibody treatment reduces age-related inflammatory responses and CD8 T cell cytotoxicity after traumatic brain injury in mice.

Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities

This study identifies RAS/PI3K pathway activation as a common driver in oncogene-negative lung adenocarcinomas and shows these tumors are vulnerable to targeted therapy.

Genetic diversity loss in the Anthropocene

The paper introduces a mathematical framework to estimate genetic diversity loss due to habitat reduction and shows that over 10% of genetic diversity may already be lost globally.

Ultrasound mediated cellular deflection results in cellular depolarization

This study shows ultrasound causes cellular membrane deflection and depolarization in neurons and fibroblasts using high-speed imaging and electrophysiology.

Irradiated mesenchymal stromal cells induce genetic instability in human CD34+ cells

The paper shows that irradiated mesenchymal stromal cells cause genetic instability in CD34+ cells through genotoxic signaling and reactive oxygen species.

CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

This study identifies CEP78's role in ciliogenesis by showing it interacts with CEP350 and the EDD1 ubiquitin ligase complex to regulate CP110 levels.

Validation of a low-cost, carbon dioxide-based cryoablation system for percutaneous tumor ablation

This paper validates a low-cost cryoablation system using carbon dioxide for tumor ablation in resource-constrained settings, showing effective necrosis in rat and porcine models.

Genetic dissection of an ancient divergence in yeast thermotolerance

This study identifies eight housekeeping genes responsible for Saccharomyces cerevisiae's thermotolerance advantage over S. paradoxus using a new mapping approach in a sterile hybrid.