Cell BiologybioRxiv
The dCMP deaminase DCTD and the E3 ligase TOPORS are central mediators of decitabine cytotoxicity
C. J. Carnie, M. J. Gotz, C. S. Palma-Chaundler…·S. P. Jackson
This study identifies DCTD and TOPORS as key factors in decitabine cytotoxicity by showing their roles in DPC formation and repair.
DOI 10.1038/s44318-024-00108-2