Author

C. J. Dickson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. A. Golosov· 1 shared A. Acharya· 1 shared A. Kovalevsky· 1 shared A. Pavlova· 1 shared C. Chipot· 1 shared C. J. Schwalen· 1 shared C. Molteni· 1 shared C. Velez-Vega· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

A. A. Golosov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Scorpion α-toxin LqhαIT specifically interacts with a glycan at the pore domain of voltage-gated sodium channels

S. Phulera, C. J. Dickson, C. J. Schwalen, M. Khoshouei, S. J. Cassell, Y. Sun, T. Condos, J. Whicher, W. A. Weihofen

This study determines the cryo-EM structure of LqhIT bound to NavPas, revealing its interaction with a glycan at the pore domain and its mechanism of action.

bioRxiv · Jan 26, 2024Biophysics

Combined free energy calculation and machine learning methods for understanding ligand unbinding kinetics

M. Badaoui, P. J. Buigues, D. Berta, G. M. Mandana, H. Gu, T. Földes, C. J. Dickson, V. Hornak, M. Kato, C. Molteni, S. D. Parsons, E. Rosta

This paper develops a computational method combining free energy calculations and machine learning to predict ligand unbinding kinetics and identify key interactions for drug design.

bioRxiv · Sep 8, 2021Biophysics

Inhibitor binding influences the protonation states of histidines in SARS-CoV-2 main protease

A. Pavlova, D. L. Lynch, I. Daidone, L. Zanetti-Polzi, M. D. Smith, C. Chipot, D. W. Kneller, A. Kovalevsky, L. Coates, A. A. Golosov, C. J. Dickson, C. Velez-Vega, J. S. Duca, J. V. Vermaas, Y. T. Pang, , J. C. Gumbart

This study uses molecular dynamics simulations to investigate how inhibitor binding affects the protonation states of histidines in SARS-CoV-2 main protease, showing their impact on structural stability and inhibitor binding.

bioRxiv · Sep 7, 2020Biophysics