Author

C. J. Halkes

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Otte· 1 shared E. B. van den Akker· 1 shared E. O. Karakaslar· 1 shared E. Sanchez-Lopez· 1 shared H. Veelken· 1 shared J. F. Severens· 1 shared J. J. van Dongen· 1 shared M. Griffioen· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperCancer Biology

A. M. Otte

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 9, 2022

Single cell guided deconvolution of bulk transcriptomics recapitulates differentiation stages of acute myeloid leukemia and predicts drug response

E. O. Karakaslar, J. F. Severens, E. Sanchez-Lopez…·E. B. van den Akker

This study uses single-cell data to deconvolute bulk RNA-seq samples of AML, showing that differentiation stages can be reconstructed and used to predict drug responses like Venetoclax resistance.

DOI 10.1101/2022.12.09.519738

humanbulk RNA-seq

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