Cell BiologyScience AdvancesPeer-reviewed
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.
P. Hari, F. R. Millar, N. Tarrats…·J. C. Acosta
This study identifies TLR2 as a key mediator of oncogene-induced senescence by promoting cell cycle arrest and regulating the senescence-associated secretory phenotype through DAMPs.
DOI 10.1126/sciadv.aaw0254