Author

C. Jean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Pain· 2 shared A. Brunel· 1 shared A. M. Barrie· 1 shared A. M. Mark· 1 shared A. Molinolo· 1 shared B. Gyorffy· 1 shared B. Horvat· 1 shared C. Baquerre· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

B. Pain

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Author profile →

4 papers

Recent·Most cited

Translatome-based classification reveals a dual metabolic dependency of a new tumor subtype of pancreatic cancer.

S. Shin, R. Nicolle, C. Jean, R. Samain, M. Ayadi, J. Raffenne, A. Brunel, J. Solorzano, C. Neuzillet, C. Joffre, S. Rocchi, J. Iovanna, N. J. Dusetti, O. Larsson, S. Pyronnet, , Y. Martineau

The paper identifies a new pancreatic cancer subtype with low protein synthesis but high integrated stress response activation, linked to metabolic impairments and drug resistance.

bioRxiv · Dec 23, 2020Cancer Biology

Reprogrammed Pteropus Bat Stem Cells Present Distinct Immune Signature And Are Highly Permissive For Henipaviruses

N. Aurine, C. Baquerre, M. Gaudino, C. Jean, C. Dumont, S. Gervier, C. Kress, B. Horvat, B. Pain

The paper generates reprogrammed bat stem cells with a unique immune signature and high permissiveness to Henipaviruses, enabling study of virus-bat interactions.

bioRxiv · Nov 30, 2019 · PreprintCell Biology

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

C. J. Diaz Osterman, D. Ozmadenci, E. G. Kleinschmidt, K. N. Taylor, A. M. Barrie, S. Jiang, L. M. Bean, F. J. Sulzmaier, C. Jean, I. Tancioni, K. Anderson, S. Uryu, E. A. Cordasco, J. Li, X. L. Chen, , D. D. Schlaepfer

This study identifies FAK activity as a driver of platinum resistance in ovarian cancer by sustaining CSC survival and DNA repair, showing that FAK inhibitors combined with platinum can overcome resistance.

bioRxiv · Mar 30, 2019Cancer Biology

Three-dimensional culture of chicken primordial germ cells in chemically defined media containing the functional polymer FP003

B. Pain, C. Jean, Y.-C. Chen, W.-C. CHANG, S.-P. Lin, S. Rival-Gervier, M. MINAMI, H. HAYASHI, T. KANAKI, S.-C. WU

This study develops a 3D culture system for chicken primordial germ cells using chemically defined media, enabling scalable expansion and maintenance of cellular properties.

bioRxiv · Jun 29, 2018Cell Biology