A Photoactivated Protein Degrader for Optical Control of Synaptic Function
Tak Ko, C. Jou, Alejandro Borja Grau-Perales, Martin Reynders, André Antonio Fenton, Dirk H. Trauner
This paper introduces PHOTACs, a method to optically degrade specific proteins in brain tissue, and demonstrates its effectiveness in reducing synaptic function in mice.
bioRxiv · Feb 13, 2023 · PreprintNeuroscience