M. Vidal

Quantifying massively parallel microbial growth with spatially mediated interactions

The paper quantifies microbial growth variability across spatial locations using machine learning and develops a spatial consumer-resource model to explain growth patterns and infer intrinsic growth parameters.

CellSeg3D: self-supervised 3D cell segmentation for fluorescence microscopy

CellSeg3D introduces self-supervised 3D cell segmentation models for fluorescence microscopy, achieving performance comparable to supervised methods without requiring ground truth labels.

A comprehensive two-hybrid analysis to explore the L. pneumophila effector-effector interactome

The paper uses a yeast two-hybrid screen to identify novel effector-effector interactions in L. pneumophila, doubling the known number of such interactions.

Modelling single-stress omics integration with HIVE enables the identification of responding signatures to multifactorial stress combinations in plants

HIVE integrates single-stress transcriptomics data to identify gene signatures responding to multifactorial stress combinations in plants.

Pervasive mislocalization of pathogenic coding variants underlying human disorders

The paper develops a high-throughput imaging platform to assess the functional impact of missense variants on protein localization, finding that mislocalization is common in pathogenic variants.

Next-generation large-scale binary protein interaction network for Drosophila

The paper generates a high-confidence binary protein interaction network for Drosophila using yeast two-hybrid screens and integrates it with existing data to create a comprehensive reference network.

Validation of a novel immersive Virtual Reality setup with responses of wild-caught freely-moving coral reef fish

This study validates a novel immersive VR setup by analyzing the behavioral responses of convict surgeonfish to virtual stimuli, revealing their visual cue preferences during recruitment.

The reproductive status of the host determines the tolerance and resistance to Mycobacterium marinum infection in Drosophila melanogaster

This study investigates how the reproductive status of Drosophila melanogaster affects its tolerance and resistance to Mycobacterium marinum infection, identifying key immune pathways and gene expressions involved.

Drosophila larval models of invasive tumourigenesis for in vivo studies on tumour/peripheral host tissue interactions during cancer cachexia.

This study uses Drosophila larval models to investigate tumour/host tissue interactions in cancer cachexia, showing that specific genetic factors drive tissue wasting rather than general tumour burden or malnutrition.

Plasmodium falciparum and helminth coinfections increase IgE and parasite-specific IgG responses

This study examines how co-infections with Plasmodium falciparum and helminths affect antibody responses in Mozambican individuals, finding increased IgE and IgG levels in co-infected individuals.

Antibody Conversion rates to SARS-CoV-2 in Saliva from Children Attending Summer Schools in Barcelona, Spain

The paper assesses SARS-CoV-2 antibody conversion rates in children and adults via saliva samples, finding higher conversion in adults and a protective role of anti-spike antibodies.

Exosomal melanotransferrin as a potential biomarker for metastatic melanoma

This paper identifies exosomal melanotransferrin as a potential noninvasive biomarker for metastatic melanoma by demonstrating its detection in plasma samples using an ELISA.

Exostosin-1 Glycosyltransferase Regulates Endoplasmic Reticulum Architecture and Dynamics

This study shows that Exostosin-1 glycosyltransferase regulates ER morphology and dynamics, affecting cell size and metabolic processes in mammalian cells.

Reduced placental transfer of antibodies against microbial and vaccine antigens in HIV-infected women in Mozambique

The paper measures antibody transfer from HIV-infected mothers to infants in Mozambique and finds HIV reduces placental transfer of IgG and IgG1 antibodies against pathogens and vaccine antigens.

Highly sensitive and specific multiplex antibody assays to quantify immunoglobulins M, A and G against SARS-CoV-2 antigens

The paper develops and validates multiplex antibody assays to quantify IgM, IgA, and IgG against SARS-CoV-2 antigens, showing high specificity and sensitivity for detecting immune responses.

Genomic characterization of the non-O1/non-O139 Vibrio cholerae strain that caused a gastroenteritis outbreak in Santiago, Chile, 2018

The paper characterizes a non-O1/non-O139 Vibrio cholerae outbreak strain in Chile, finding it lacks classical virulence genes but carries virulence-associated genomic islands.

The antimicrobial peptide Defensin cooperates with Tumour Necrosis Factor to drive tumour cell death in Drosophila

This study shows Defensin, an antimicrobial peptide, works with Tumour Necrosis Factor to kill tumour cells in Drosophila, demonstrating an in vivo anti-cancer role for an endogenous AMP.