Cell BiologybioRxiv
Post-injury hydraulic fracturing drives fissure formation in the zebrafish basal epidermal cell layer
A. S. Kennard, M. Sathe, E. C. Labuz…·J. A. Theriot
This study shows that zebrafish epidermis forms fissures post-injury due to hydraulic fracturing driven by osmotic pressure, with myosin II involvement and fluid clearance via macropinocytosis.