Author

C. Koh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Hardy· 1 shared A. Henrion Lacritick· 1 shared A. M. Brown· 1 shared A. Petrin· 1 shared A. Sebastian· 1 shared B. Chamberlain· 1 shared B. K. Allen· 1 shared B. Tesar· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Hardy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Design of a systemic small molecule clinical STING agonist using physics-based simulations and artificial intelligence

B. K. Allen, M. M. Kulkarni, B. Chamberlain, T. Dwight, C. Koh, R. Samant, F. Jernigan, J. Rice, D. Tan, S. Li, K. Marino, H. Huang, E. Chiswick, B. Tesar, S. Sparks, , W. Sherman

This paper designs a small molecule STING agonist, SNX281, using computational methods and AI, showing systemic activity and antitumor effects in mice.

bioRxiv · May 23, 2022 · PreprintCancer Biology

The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito

F. Roesch, C. Cereghino, L. Carrau, A. Hardy, H. Ribeiro-Filho, A. Henrion Lacritick, C. Koh, J. Marano, T. A. Bates, P. Rai, C. Chuong, S. Akter, T. Vallet, H. Blanc, T. Elliot, , J. Weger-Lucarelli

This paper identifies a mutation in the E2 glycoprotein of Mayaro virus that enhances transmission in Aedes aegypti but reduces replication in human cells, suggesting a trade-off in host adaptation.

bioRxiv · Apr 5, 2022 · PreprintMicrobiology

Artificial selection finds new hypotheses for the mechanism of Wolbachia-mediated dengue blocking in mosquitoes

S. A. Ford, I. Albert, S. L. Allen, S. Chenoweth, M. Jones, C. Koh, A. Sebastian, L. T. Sigle, E. A. McGraw

The paper uses artificial selection to identify genetic variations linked to Wolbachia-mediated dengue blocking in mosquitoes and proposes hypotheses about the underlying mechanisms.

bioRxiv · Nov 25, 2019Evolutionary Biology