Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections
L. N. McKinley, M. O. Meyer, A. Sebastian, B. K. Chang, K. J. Messina, I. Albert, P. C. Bevilacqua
The paper tests over 2,600 natural twister ribozymes using CHiTA, finding 94% are active and showing structural tolerance.
bioRxiv · Jul 11, 2024Biochemistry