C. Laflamme

The identification of potent and selective antibodies for Serine/threonine-protein kinase TBK1, for use in immunoblot, immunofluorescence and immunoprecipitation

The paper evaluates 11 commercial antibodies for TBK1 detection in immunoblot, immunofluorescence, and immunoprecipitation using a knock-out cell line to identify potent and selective antibodies.

IgG-aggregates rapidly up-regulate FcgRI expression at the surface of human neutrophils in a FcgRII-dependent fashion: A crucial role for FcgRI in the generation of reactive oxygen species.

This study shows that IgG-aggregates rapidly increase FcgRI expression on human neutrophils, mediated by FcgRIIa, and that FcgRI is essential for ROS production in response to immune complexes.