Author

E. Boilard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

I. Allaeys· 2 shared J. E. Italiano· 2 shared K. R. Machlus· 2 shared P. Cunin· 2 shared A. E. Bentlage· 1 shared A. Gravel· 1 shared A. J. Murphy· 1 shared A. Morris· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

I. Allaeys

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

IgG hexamers initiate acute lung injury

S. J. Cleary, Y. Seo, J. J. Tian, N. Kwaan, D. P. Bulkley, A. E. Bentlage, G. Vidarsson, E. Boilard, R. Spirig, J. C. Zimring, M. R. Looney

This study shows that IgG hexamerization is critical for triggering acute lung injury and suggests therapeutic strategies targeting hexamer formation.

bioRxiv · Jan 24, 2024Immunology

Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36

M. N. Barrachina, G. Pernes, I. C. Becker, I. Allaeys, T. I. Hirsch, D. J. Groeneveld, A. O. Khan, D. Freire, K. Guo, E. Carminita, P. K. Morgan, T. J. Collins, N. Mellett, Z. Wei, I. Almazni, , K. R. Machlus

This study identifies the role of phospholipid remodeling and PUFA uptake via CD36 in megakaryopoiesis and platelet production, showing dietary fatty acids impact platelet counts.

bioRxiv · Feb 12, 2023Cell Biology

SARS-CoV-2 type I Interferon modulation by non structural proteins 1 and 2

L. Flamand, E. Lacasse, I. Dubuc, I. Allaeys, L. Gudimard, A. Gravel, E. Boilard

This study investigates how SARS-CoV-2 and its variants modulate type I interferon responses through non-structural proteins 1 and 2, showing differential effects on IFN production and NF-κB-driven inflammation.

bioRxiv · Jun 9, 2022 · PreprintMicrobiology

IgG-aggregates rapidly up-regulate FcgRI expression at the surface of human neutrophils in a FcgRII-dependent fashion: A crucial role for FcgRI in the generation of reactive oxygen species.

S. Huot, C. Laflamme, P. R. Fortin, E. Boilard, M. Pouliot

This study shows that IgG-aggregates rapidly increase FcgRI expression on human neutrophils, mediated by FcgRIIa, and that FcgRI is essential for ROS production in response to immune complexes.

bioRxiv · Mar 4, 2020Immunology

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

P. Cunin, R. Bouslama, K. R. Machlus, M. Martinez-Bonet, P. Y. Lee, N. Nelson-Maney, A. Morris, L. Guo, A. S. Weyrich, M. Sola-Visner, E. Boilard, J. E. Italiano, P. A. Nigrovic

The paper shows that emperipolesis allows neutrophils to transfer membrane to platelets via megakaryocytes, contributing to platelet production and membrane content.

bioRxiv · Dec 21, 2018Cell Biology

Differential attenuation of β2 integrin-dependent and -independent neutrophil migration by Ly6G ligation

P. Cunin, P. Lee, E. Kim, A. Schmider, N. Cloutier, A. Pare, M. Gunzer, R. Soberman, S. Lacroix, E. Boilard, C. Lefort, P. Nigrovic

This study shows that Ly6G ligation selectively inhibits β2 integrin-dependent neutrophil migration in specific inflammatory contexts.

bioRxiv · Nov 1, 2018Immunology