Spheroid culture of mesenchymal stromal cells results in morpho-rheological properties appropriate for improved microcirculation
S. Tietze, M. Krater, A. Jacobi, A. Taubenberger, M. Herbig, R. Wehner, M. Schmitz, O. Otto, C. List, B. Kaya, M. Wobus, M. Bornhauser, J. Guck
This study shows that culturing mesenchymal stromal cells in 3D spheroids improves their morpho-rheological properties, enhancing their ability to circulate through microvascular networks.
bioRxiv · Oct 11, 2018Biophysics