Author

M. Bornhauser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Jacobi· 2 shared B. Lowenberg· 2 shared H. Altmann· 2 shared J. F. DiPersio· 2 shared J. Guck· 2 shared J. K. Davidson-Moncada· 2 shared J. Muth· 2 shared J. Vadakekolathu· 2 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

A. Jacobi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TP53 abnormalities correlate with immune infiltration and are associated with response to flotetuzumab, an investigational immunotherapy, in acute myeloid leukemia

C. Lai, J. Vadakekolathu, S. Reeder, S. E. Church, T. Hood, I. Aldoss, J. Godwin, M. J. Wieduwilt, M. Arellano, J. Muth, F. Ravandi, K. Sweet, H. Altmann, G. A. Foulds, F. Stolzel, , S. Rutella

This paper shows TP53 mutations in AML are linked to immune features and improved response to flotetuzumab immunotherapy.

bioRxiv · Feb 28, 2020 · PreprintImmunology

Immune Landscapes Predict Chemotherapy Resistance And Immunotherapy Response In Acute Myeloid Leukemia

J. Vadakekolathu, M. D. Minden, T. Hood, S. E. Church, S. Reeder, H. Altmann, A. H. Sullivan, E. J. Viboch, T. Patel, N. Ibrahimova, S. E. Warren, A. Arruda, Y. Liang, J. Muth, M. Schmitz, , S. Rutella

This study identifies immune subtypes in AML and shows that IFN-gamma profiles predict chemotherapy resistance and immunotherapy response.

bioRxiv · Jul 26, 2019Immunology

Spheroid culture of mesenchymal stromal cells results in morpho-rheological properties appropriate for improved microcirculation

S. Tietze, M. Krater, A. Jacobi, A. Taubenberger, M. Herbig, R. Wehner, M. Schmitz, O. Otto, C. List, B. Kaya, M. Wobus, M. Bornhauser, J. Guck

This study shows that culturing mesenchymal stromal cells in 3D spheroids improves their morpho-rheological properties, enhancing their ability to circulate through microvascular networks.

bioRxiv · Oct 11, 2018Biophysics

Detection Of Human Disease Conditions By Single-Cell Morpho-Rheological Phenotyping Of Whole Blood

N. Toepfner, C. Herold, O. Otto, P. Rosendahl, A. Jacobi, M. Krater, J. Stachele, L. Menschner, M. Herbig, L. Ciuffreda, L. Ranford-Cartwright, M. Grzybek, U. Coskun, E. Reithuber, G. Garriss, , J. Guck

This paper introduces a method to detect human disease conditions by analyzing whole blood using morpho-rheological phenotyping without labeling or separation.

bioRxiv · Jun 1, 2017Biophysics