Author

C. Lo Celso

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:imaging· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. Adams· 2 shared K. Duffy· 2 shared S. Gonzalez Anton· 2 shared A. Blagborough· 1 shared A. Lipien· 1 shared A. Marra· 1 shared B. Falini· 1 shared B. Gottgens· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

G. Adams

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PACESS: Practical AI-based Cell Extraction and Spatial Statistics for large 3D bone marrow tissue images

G. Adams, F. Tissot, C. Liu, C. Brunsdon, K. Duffy, C. Lo Celso

PACESS analyzes 3D bone marrow images to study spatial interactions between cell types, revealing new microenvironments influenced by leukemic cell clusters.

bioRxiv · Dec 29, 2022Cell Biology

Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells

B. Partridge, S. Gonzalez Anton, R. Khorshed, G. Adams, C. Pospori, C. Lo Celso, C. F. Lee

The paper analyzes MPP cell trajectories from in-vivo imaging, identifies transient non-Gaussian super-diffusion, and explains it using a run-and-tumble model.

bioRxiv · Nov 19, 2021Biophysics

The metalloproteinase inhibitor Prinomastat reduces AML growth,prevents stem cell loss and improves chemotherapy effectiveness

C. Pirillo, M. Haltalli, S. Gonzalez Anton, V. Tini, I. Kong, E. Hawkins, B. Falini, A. Marra, D. Duarte, C. Lo Celso

This study shows that prinomastat, an MMP inhibitor, reduces AML growth, prevents stem cell loss, and enhances chemotherapy effectiveness in a mouse model.

bioRxiv · Dec 1, 2020 · PreprintCancer Biology

Malaria-induced remodelling of the bone marrow microenvironment mediates loss of haematopoietic stem cell function

M. L. Haltalli, S. Watcham, N. K. Wilson, K. Eilers, A. Lipien, M. L. Vainieri, N. Ruivo, H. Ang, R. E. Sinden, K. Duffy, B. Gottgens, A. Blagborough, C. Lo Celso

This study investigates how malaria infection alters the bone marrow microenvironment, leading to impaired haematopoietic stem cell function through changes in endothelium and osteoblasts.

bioRxiv · Nov 22, 2018 · PreprintCell Biology