Author

C. F. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Y. A. Chiao· 2 shared A. Cairoli· 1 shared A. Chakraborty· 1 shared A. D. Chakraborty· 1 shared A. Spenlehauer· 1 shared B. Partridge· 1 shared C. Light· 1 shared C. Lo Celso· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

Y. A. Chiao

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Late-life Rapamycin Treatment Enhances Cardiomyocyte Relaxation Kinetics and Reduces Myocardial Stiffness

A. D. Chakraborty, K. Kooiker, K. A. Kobak, Y. Cheng, C. F. Lee, M. Razumova, H. Granzier, M. Regnier, P. S. Rabinovitch, F. Moussavi-Harami, Y. A. Chiao

This study shows that late-life rapamycin treatment improves cardiomyocyte relaxation and reduces myocardial stiffness in aged mice, reversing diastolic dysfunction.

bioRxiv · Jun 12, 2023 · PreprintPhysiology

Model of inverse bleb growth explains giant vacuole dynamics during cell mechanoadaptation

A. Cairoli, A. Spenlehauer, D. D. Overby, C. F. Lee

The paper models inverse bleb growth to explain giant vacuole dynamics during cell mechanoadaptation, showing how membrane mechanics and pressure affect vacuole formation and competition.

bioRxiv · Jun 26, 2022Biophysics

Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells

B. Partridge, S. Gonzalez Anton, R. Khorshed, G. Adams, C. Pospori, C. Lo Celso, C. F. Lee

The paper analyzes MPP cell trajectories from in-vivo imaging, identifies transient non-Gaussian super-diffusion, and explains it using a run-and-tumble model.

bioRxiv · Nov 19, 2021Biophysics

NAD+ Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy

Y. A. Chiao, A. Chakraborty, C. Light, R. Tian, J. Sadoshima, X. Shi, H. Gu, C. F. Lee

This study shows that NAD+ redox imbalance worsens diabetic cardiomyopathy by impairing cardiomyocyte function and suggests NAMPT as a therapeutic target.

bioRxiv · Jul 3, 2020Physiology